Skincare Is Missing the System That Brings It All Home

Why the endocannabinoid system belongs in every serious conversation about skin By Mandy Lile | Licensed aesthetician and founder of POTENCY No. 710 After 30 years in skincare, I am still amazed by what this industry is willing to examine and what it chooses to ignore. We will study ingredients, devices, peptides, growth factors, delivery […]
What Are TRP Channels? Meet Your Skin’s Sensory Gateways

When we talk about receptor-driven skincare, we’re really talking about communication. Your skin isn’t simply sitting there waiting for products to be applied. It’s constantly gathering information from the world around you and responding through an intricate network of receptors, channels, and signaling pathways. One fascinating part of that network is something called TRP channels. […]
Exosomes, Peptides & Cannabinoids: Conversations with Your Skin

The skincare industry has never been more fascinated with cellular communication. Everywhere you look, you’ll find products highlighting peptides, exosomes, or cannabinoids as the next breakthrough. While each represents a different approach to supporting healthy-looking skin, they all share one common idea: Skin is constantly communicating. The real question isn’t which ingredient is “best.” It’s […]




